© 2011 LipoScience Inc.
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Meet Edward*Edward is 42 years old. His son is 2 years old. He has a strong family history of heart disease—his father had a heart attack at the age of 51. Edward’s LDL cholesterol (LDL-C) level is normal, his LDL particle number (LDL-P) is very high. |
LDL Particles are linked to heart disease.
It is important to know that having a high number of LDL particles (LDL-P) is bad. They carry and deposit cholesterol into your arteries that become plaque—atherosclerosis or hardening of the arteries.
These are Edward’s Test Results
| LDL Particle | LDL Cholesterol | HDL Cholesterol | Triglycerides | Total Cholesterol |
| LDL-P mg/dL |
LDL-C mg/dL |
HDL-C mg/dL |
TG mg/dL |
TC mg/dL |
| 1809 | 94 | 24 | 142 | 146 |
| High > 1600 | Within normal limits < 130 |
Desirable > 40 |
Desirable < 150 |
Desirable < 200 |
LDL Particles Cause Plaque2
Plaque Progression: More LDL Particles = More Plaque
The higher the number of LDL particles, the greater the likelihood for them to enter the arterial wall and deposit their contents forming atherosclerotic plaque. Measurement of LDL-C on traditional lipid panels does not reflect LDL particle number.
Click HERE to download a PDF of LDL Particles Cause Plaque.
*These case studies represent patients with conditions contributing to cardiometabolic risk and have been provided by clinicians who use the NMR LipoProfile® test routinely in their practices. These case studies are for informational purposes only and not for diagnostic use.
1. LDL-P Ranges are demonstrated in a representative sampling of the general population (n=5,362) enrolled in the Multi-Ethnic Study of Atherosclerosis (MESA). Mora S, Szklo M, Otvos JD, Greenland P, et al. LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2007;192:211-217. Each reporting laboratory should verify the validity of these values for the population it serves.
2. Brunzell JD, Davidson M, Furberg, CD, et al. LipoProtein Management in Patients with Cardiometabolic Risk. J. Am Coll. Cardiol. 2008;51;1512-24
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Meet Theresa*Theresa is 56 and retired last year to help take care of her granddaughter. She has diabetes and is being treated for high blood pressure. Theresa’s LDL cholesterol (LDL-C) is normal, but her LDL particle number (LDL-P) is high. |
LDL Particles are linked to heart disease.
It is important to know that having a high number of LDL particles is bad. They carry and deposit cholesterol into your arteries that become plaque—atherosclerosis or hardening of the arteries
These are Theresa’s Test Results
| LDL Particle | LDL Cholesterol | HDL Cholesterol | Triglycerides | Total Cholesterol |
| LDL-P mg/dL |
LDL-C mg/dL |
HDL-C mg/dL |
TG mg/dL |
TC mg/dL |
| 1611 | 98 | 68 | 199 | 206 |
| High > 1600 | Within normal limits < 130 |
Desirable > 40 |
Desirable < 150 |
Desirable < 200 |
LDL Particles Cause Plaque2
Plaque Progression: More LDL Particles = More Plaque
The higher the number of LDL particles, the greater the likelihood for them to enter the arterial wall and deposit their contents forming atherosclerotic plaque. Measurement of LDL-C on traditional lipid panels does not reflect LDL particle number.
Click HERE to download a PDF of LDL Particles Cause Plaque.
*These case studies represent patients with conditions contributing to cardiometabolic risk and have been provided by clinicians who use the NMR LipoProfile® test routinely in their practices. These case studies are for informational purposes only and not for diagnostic use.
1. LDL-P Ranges are demonstrated in a representative sampling of the general population (n=5,362) enrolled in the Multi-Ethnic Study of Atherosclerosis (MESA). Mora S, Szklo M, Otvos JD, Greenland P, et al. LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2007;192:211-217. Each reporting laboratory should verify the validity of these values for the population it serves.
2. Brunzell JD, Davidson M, Furberg, CD, et al. LipoProtein Management in Patients with Cardiometabolic Risk. J. Am Coll. Cardiol. 2008;51;1512-24
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Meet Lee*Lee is 60 years old. He has hypertension and dyslipoproteinemia. Lee’s LDL cholesterol (LDL-C) level is normal, but his LDL particle number (LDL-P) is high. |
LDL Particles are linked to heart disease.
It is important to know that having a high number of LDL particles (LDL-P) is bad. They carry and deposit cholesterol into your arteries that become plaque—atherosclerosis or hardening of the arteries.
These are LEE’s Test Results
| LDL Particle | LDL Cholesterol | HDL Cholesterol | Triglycerides | Total Cholesterol |
| LDL-P mg/dL |
LDL-C mg/dL |
HDL-C mg/dL |
TG mg/dL |
TC mg/dL |
| 1459 | 80 | 62 | 79 | 158 |
| High > 1600 | Within normal limits < 130 |
Desirable > 40 |
Desirable < 150 |
Desirable < 200 |
LDL Particles Cause Plaque2
Plaque Progression: More LDL Particles = More Plaque
The higher the number of LDL particles, the greater the likelihood for them to enter the arterial wall and deposit their contents forming atherosclerotic plaque. Measurement of LDL-C on traditional lipid panels does not reflect LDL particle number.
Click HERE to download a PDF of LDL Particles Cause Plaque.
*These case studies represent patients with conditions contributing to cardiometabolic risk and have been provided by clinicians who use the NMR LipoProfile® test routinely in their practices. These case studies are for informational purposes only and not for diagnostic use.
1. LDL-P Ranges are demonstrated in a representative sampling of the general population (n=5,362) enrolled in the Multi-Ethnic Study of Atherosclerosis (MESA). Mora S, Szklo M, Otvos JD, Greenland P, et al. LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis 2007;192:211-217. Each reporting laboratory should verify the validity of these values for the population it serves.
2. Brunzell JD, Davidson M, Furberg, CD, et al. LipoProtein Management in Patients with Cardiometabolic Risk. J. Am Coll. Cardiol. 2008;51;1512-24